Comparative Study of Hepatic Changes in Patients of Metabolic Syndrome and Chronic Alcoholism

Aims and Objective: Comparative study of hepatic changes in patients of metabolic syndrome and chronic alcoholism. Material and Method: The material of the study included 30 metabolic syndrome patients and 30 chronic alcoholics selected from the medicine outdoor clinic (including diabetic clinic) and medicine indoor wards as well as from GI clinic of Postgraduate Department of Medicine, S.N. Medical College and Hospital Agra . Results: Most metabolic syndrome patients (60%) as well as chronic alcoholics (50%) were asymptomatic. Anorexia and fatigue/ malaise was present in 13.3% and 40% respectively in metabolic syndrome patients as compared to anorexia (30%) and fatigue / malaise (50%) in chronic alcoholics. Nausea / vomiting and right upper abdominal quadrant pain was present in 10% metabolic syndrome patients as compared Nausea / vomiting (40%) and Right upper abdominal quadrant pain(26.6%) in chronic alcoholics. Hepatomegaly and icterus was present in 23.3% and 10% respectively in metabolic syndrome patients as compared hepatomegaly (80%) and icterus (60%) in chronic alcoholics. Ascites and upper GI bleeding was present in 13.3% and 6.7% metabolic syndrome patients respectively as compared to ascites (50%) and upper GI bleeding (9%) in chronic